Yellow spot disease or age-related macular degeneration; is the loss of central vision as a result of the progressive loss of receptor cells in the macula region (yellow spot) in the retina layer of the eye, which is responsible for the clearest vision. In people who develop macular degeneration, vision loss begins in the center of the visual field and the lost visual field develops towards the edges as the cells disappear over time. In other words, patients have a ring-shaped vision at the edges while seeing a dark spot in the center. Although patients do not lose their vision completely; severely affected in terms of quality of life.